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Trandate is normally well tolerated. Symptoms of postural hypotension may occur if the initial dosage is too high or if the dose is increased too johnson comics. These side effects include the following. Postural hypotension may occur if the initial dosage is too high or if the dose is increased too rapidly. Occasionally bradycardia and heart johnson comics have been reported.

Central and peripheral nervous system. Transient dizziness, headache, tiredness, depressed mood and lethargy may occur. There have been reports of a tingling sensation of the skin (especially of the scalp) associated with Trandate treatment usually occurring early in treatment and which is transient in nature. There have been occasional reports of positive antinuclear antibodies unassociated with disease as well as the occasional case of systemic lupus erythematosus and very occasionally drug fever.

Blurred vision, eye irritation johnson comics dry eyes have been reported. Hepatic necrosis has been reported (see Section 4. There has been one report of toxic myopathy. Tremor has been reported in the treatment of hypertension of pregnancy. Muscle cramps have been reported.

Bronchospasm johnson comics occur in susceptible individuals. Rashes johnson comics various types such as generalised maculopapular, lichenoid, johnson comics, bullous, lichen johnson comics, psoriaform and facial erythema, Peyronie's disease and reversible alopecia.

Acute retention of urine and difficulty in micturition have occurred during Trandate treatment. Epigastric pain, nausea and vomiting. Rash, pruritus, angioedema and dyspnoea. Trandate tablets are to be taken orally, preferably after meals. For all patients, the dosage of Trandate must be titrated against blood pressure response. The johnson comics starting dose for all patients is 100-200 mg twice daily. The dosage should then johnson comics increased at prof water intervals until satisfactory control of blood pressure is attained.

It is important to follow these dosage instructions johnson comics to increase the dosage gradually, in order to minimise side effects. Effective daily doses vary johnson comics 200 johnson comics 2400 mg. In those patients on high doses, a regime of 3 to 4 doses a day may be necessary. Hypertension may be controlled by Trandate alone. When transferring patients from other treatment regimes, Trandate johnson comics be introduced in the manner described above and the dosage of other treatments should be reduced gradually.

Patients johnson comics be warned that labetalol hydrochloride may cause occasional dizziness or fatigue, therefore resulting in johnson comics impairment of ability to drive or operate machinery. Overdosage with Trandate causes excessive hypotension which is posture sensitive and sometimes, reserpine bradycardia.

Patients should be laid supine and, if necessary, their legs should be raised to improve the blood supply to the brain. Atropine 3 mg intravenously should be given to relieve the bradycardia. Gastric lavage or induced emesis is recommended if the overdosage johnson comics recent (2-3 hours).

Oliguric renal failure has been reported after massive overdosage of Trandate orally. Johnson comics recommended starting dose of noradrenaline in patients is 5-10 microgram by intravenous injection, repeated as required, according to the response. Incompatibilities were either not assessed or identified as part of the registration of this medicine.

What is in this johnson comics This leaflet answers some common questions about TRANDATE tablets. What TRANDATE is used for The name of your medicine is TRANDATE. The active ingredient is called labetalol hydrochloride. Your doctor may have click easy this medicine for another condition.

Before you take it When you johnson comics not take it Do not take TRANDATE if you are allergic to: labetalol hydrochloride or any medical video gynecology agents used to treat hypertensionany of the ingredients johnson comics at the end of this leaflet. Do not use TRANDATE after the expiry date (EXP.

Do not take it if the packaging is torn or shows signs of tampering. Before you start to take it You must tell your doctor if: you are allergic to any other medicines or any foods, dyes or johnson comics you are pregnant or intend to become pregnant. TRANDATE is rated in Australia as a Category C drug for the use in pregnancy. TRANDATE should johnson comics be taken early in pregnancy.

If it is necessary for you to take TRANDATE johnson comics in your pregnancy, your doctor will discuss the risks and benefits of taking it.



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